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Publications by OCMS Members and staff

1999/2000

* indicates OCMS author

  1. The nicotonic acetylcholine receptor: from molecular model to single channel conductance. Adcock C, Smith GR & Sansom MSP*, Eur Biophys J 29, 9-37 2000.
  2. A versatile synthetic route to quinoxaline, pyrazine and 1,2,4-triazine substituted a-amino acids from vicinal tricarbonyls. Adlington RM, Baldwin JE*, Catterick D & Pritchard GJ, J Chem Soc Perkin Trans I (3), 299 - 302 2000.
  3. The synthesis of novel heterocyclic substituted a-amino acids; further exploitation of a-amino acid alkynyl ketones. Adlington RM, Baldwin JE*, Catterick D, Pritchard GJ & Tang LT, J Chem Soc Perkin Trans I (3), 303 - 305 2000.
  4. The synthesis of novel heterocyclic substituted a-amino acids; further exploitation of a-amino acid alkynyl ketones as reactive substrates. Adlington RM, Baldwin JE*, Catterick D, Pritchard GJ & Tang LT, J Chem Soc Perkin Trans I (15), 2311-2316 2000.
  5. Towards a biomimetic synthesis of the marine alkaloids papuamine and haliclonadiamine: Model studies. Adlington RM, Baldwin JE*, Challis GL, Cox RJ & Pritchard GJ, Tetrahedron 56(4), 623-628 2000.
  6. Synthesis of novel C-nucleosides with potential applications in combinatorial and parallel synthesis. Adlington RM, Baldwin JE*, Pritchard GJ & Spencer KC, Tet Lett 41(4), 575-578 2000.
  7. A biomimetic synthesis of lucidene. Adlington RM, Baldwin JE*, Pritchard GJ, Williams AJ & Watkin DJ, Org Lett 1(12), 1937-1939 1999.
  8. N-Butyldeoxygalactonojirimycin: A more selective inhibitor of glycosphingolipid biosynthesis than N-butyldeoxynojirimycin in vitro and in vivo. Andersson U, Butters TD, Dwek RA* & Platt FM, Biochem Pharmacol 59, 821-829 2000.
  9. Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles. Arris CE, Boyle FT, Calvert H, Curtin NJ, Endicott JA*, Garman EF, Gibson AE, Golding BT, Grant S, Griffin RJ, Jewsbury P, Johnson LN*, Lawrie AM, Newell DR, Noble MEM*, Sausville EA, Schultz R & Yu W, J Med Chem 43(15), 2797-2804 2000.
  10. New polyhydroxylated pyrrolizidine alkaloids from Muscari armeniacum: structural determination and biological activity. Asano N, Kuroi H, Ikeda K, Kizu H, Kameda Y, Kato A, Adachi I, Watson AA, Nash RJ & Fleet GWJ*, Tetrahedron: Asymm 11(1), 1-8 2000.
  11. Sugar-mimic glycosidase inhibitors: natural occurrence, biological activity and prospects for therapeutic application. Asano N, Nash RJ, Molyneux RJ & Fleet GWJ*, Tetrahedron: Asymm 11(8), 1645-1680 2000.
  12. Polyhydroxylated pyrrolidine and piperidine alkaloids from Adenophora triphylla var. japonica (Campanulaceae). Asano N, Nishida M, Miyauchi M, Ikeda K, Yamamoto M, Kizu H, Kameda Y, Watson AA, Nash RJ & Fleet GWJ*, Phytochemistry 53(3), 379-382 2000.
  13. Human glucose-6-phosphate dehydrogenase: the crystal structure reveals a structural NADP+ molecule and provides insights into enzyme deficiency. Au SWN, Gover S, Lam VMS & Adams MJ*, Structure 8, 293-303 2000.
  14. Adding the third dimension to virus life cycles: Three-dimensional reconstruction of icosahedral viruses from cryo-electron micrographs. Baker T, Olson NH & Fuller SD*, Microbiol Mol Biol Rev 63, 862-922 1999.
  15. Studies on the biomimetic synthesis of the manzamine alkaloids. Baldwin JE*, Claridge TDW, Culshaw AJ, Heupel FA, Lee V*, Spring DR & Whitehead RC, Chem Eur J 5(11), 3154-3161 1999.
  16. Novel C-4 heteroaromatic kainoid analogues: A parallel synthesis approach. Baldwin JE*, Fryer AM* & Pritchard GJ, Bioorganic & Medicinal Chem Lett 10(3), 309-311 2000.
  17. Preparation of 3-alkylpyridines. Formal total synthesis of haliclamines A and B. Baldwin JE*, James DA & Lee V, Tet Lett 41(5), 733-736 2000.
  18. Studies toward the biomimetic synthesis of tropolone natural products via a hetero Diels-Alder reaction. Baldwin JE*, Mayweg AVW, Neumann K & Pritchard GJ, Org Lett 1(12), 1933 -1935 1999.
  19. Synthesis of novel unsymmetrical and symmetrical diacetylenic ketones. Baldwin JE*, Pritchard GJ & Rathmell RE, Synth Comm 30(21), 3833-3847 2000.
  20. The synthesis of 4-arylsulfanyl-substituted kainoid analogues from trans-4-hydroxy-L-proline. Baldwin JE*, Pritchard GJ & Williamson DS, Bioorganic & Medicinal Chem Lett 10(17), 1927-1929 2000.
  21. Still a puzzle: why is haem covalently attached in c-type cytochromes?. Barker PD & Ferguson SJ*, Structure with Folding & Design 7(12), R281-R290 1999.
  22. A statistical mechanical method to optimize energy functions for protein folding. Bastolla U, Vendruscolo M* & Knapp EW, Proc Nat Acad Sci USA 97(8), 3977-3981 2000.
  23. Is polyproline II helix the killer conformation? A Raman optical activity study of the amyloidogenic prefibrillar intermediate of human lysozyme. Blanch EW, Morozova-Roche LA*, Cochran DAE, Doig AJ, Hecht L & Barron LD, J Mol Biol 301(2), 553-563 2000.
  24. Raman optical activity characterization of native and molten globule states of equine lysozyme: Comparison with hen lysozyme and bovine a-lactalbumin. Blanch EW, Morozova-Roche LA*, Hecht L, Noppe W & Barron LD, Biopolymers 57(4), 235-248 2000.
  25. Solution structure of a pair of modules from the gelatin-binding domain of fibronectin. Bocquier AA, Potts JR*, Pickford AR & Campbell ID*, Structure 7(12), 1451-1460 1999.
  26. Protonation of lysine residues inverts cations/anion selectivity in a model channel. Borisenko V, Sansom MSP* & Woolley CA, Biophys J 78, 1335-1348 2000.
  27. Solvent effects on the conformation of the transmembrane peptide gramicidin A: insights from electrospray ionization mass spectrometry. Bouchard M*, Benjamin DR*, Tito P*, Robinson CV* & Dobson CM*, Biophys J 78(2), 1010-1017 2000.
  28. Biophysical analysis of the insulin amyloid assembly process. Bouchard M*, Zurdo J*, Jimenez JL, Nettleton EJ*, Saibil HR, Robinson CV* & Dobson CM*, Biophys J 78(1), PLA72 2000.
  29. Formation of insulin amyloid fibrils followed by FTIR simultaneously with CD and electron microscopy. Bouchard M*, Zurdo J*, Nettleton EJ*, Dobson CM* & Robinson CV*, Protein Science 9(10), 1960-1967 2000.
  30. Mutations at critical N-glycosylation sites reduce tyrosinase activity by altering folding and quality control. Branza-Nichita N, Negroiu G, Petrescu AJ, Garman EF, Platt FM, Wormald MR, Dwek RA* & Petrescu SM, J Biol Chem 275, 8169-8175 2000.
  31. High accuracy isotope dilution analysis for the determination of ethanol using gas chromatography-combustion-isotope ratio mass spectrometry. Briche CSJW, Hernandez H*, O'Connor G, Webb KS & Catterick T, Analyst 125(12), 2189-2195 2000.
  32. Preparation of isotopically-labelled recombinant fragments of fibronectin for functional and structural study by heteronuclear nuclear magnetic resonance spectroscopy. Bright JR, Pickford AR*, Potts JR* & Campbell ID*, In: Streuli C & Grant M, ed. Extracellular Matrix Protocols. Humana Press, 56-69, Methods in Molecular Biology; vol 139. 2000.
  33. Tetrahydrofuran amino acids - versatile building blocks for unnatural biopolymers: lack of secondary structure in oligomeric carbopeptoids derived from a D-galacto-5- aminomethyltetrahydrofuran-2-carboxylic acid. Brittain DEA, Watterson MP, Claridge TDW*, Smith MD & Fleet GWJ*, J Chem Soc Perkin Trans I (21), 3655-3665 2000.
  34. Functional and structural differences between the prion protein from two alleles prnpa and prmpb of mouse. Brown DR, Iordanova IK, Wong B-S, Venien-Bryan C*, Hafiz F, Glassmith L, Sy M-S, Gambetti P, Jones I, Clive C & Haswell SJ, Eur J Biochem 267(8), 2452-2459 2000.
  35. The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases. Brown NR*, Noble MEM*, Endicott JA* & Johnson LN*, Nature Cell Biol 1(7), 438-443 1999.
  36. Crystallization and preliminary X-ray crystallographic studies on the bacteriophage F6 RNA-dependent RNA polymerase. Butcher SJ, Makeyev EV, Grimes JM, Stuart DI* & Bamford DH, Acta Cryst D 56, 1473-1475 2000.
  37. Models for molybdenum coordination during the catalytic cycle of periplasmic nitrate from Paracoccus denitrificans derived from EPR and EXAFS spectroscopy. Butler CS, Charnock JM, Bennett B, Sears HJ, Reilly AJ, Ferguson SJ*, Garner CD, Lowe DJ, Thomson AJ, Berks BC & Richardson DJ, Biochemistry 38, 9000-9012 1999.
  38. Inhibition of glycosphgolipid biosynthesis: application to lysosomal storage disorders. Butters TD, Dwek RA* & Platt FM, Chem Rev 100, 4683-4696 2000.
  39. Molecular requirements of imino sugars for the selective control of N-linked glycosylation and glycosphingolipid biosynthesis. Butters TD, van den Broeck LAGM, Fleet GWJ*, Krülle TM*, Wormald MR, Dwek RA* & Platt FM, Tetrahedron: Asymm 11(1), 113-124 2000.
  40. Neutron scattering: good news for biotechnology. Byron O & Gilbert RJC*, Current Opinion in Biotechnology 11, 72-80 2000.
  41. The solution dynamics of amyloidogenic Asp67His variant of human lysozyme: Insights from hydrogen exchange. Canet D*, Last AM*, Tito P*, Sunde M*, Spencer A*, Redfield C*, Robinson CV* & Dobson CM*, Biophys J 78(1), PLA22 2000.
  42. The Greek key protein apo-pseudoazurin folds through an obligate on-pathway intermediate. Capaldi AP, Ferguson SJ* & Radford SE, J Mol Biol 286, 1621-1632 1999.
  43. Computer modelling and simulation studies of a human inwardly rectifying potassium channel Kir6.2. Capener CE & Sansom MSP*, J Physiology 525, 79P-80P 2000.
  44. Homology modeling and molecular dynamics simulation studies of an inward rectifier potassium channel. Capener CE, Shrivastava IH, Ranatunga KM, Forrest LR, Smith GR & Sansom MSP*, Biophys J 78(6), 2929-2942 2000.
  45. Comparison of equilibrium and kinetic approaches for determining protein folding mechanisms. Chamberlain AK* & Marqusee S, In: Protein Folding Mechanisms. Academic Press, 283-328, Advances in Protein Chemistry; vol 53. 2000.
  46. Mutational analysis of the propensity for amyloid formation by a globular protein. Chiti F*, Taddei N, Bucciantini M, White P, Ramponi G & Dobson CM*, EMBO J 19(7), 1441-1449 2000.
  47. Mutational analysis of acylphosphatase suggests the importance of topology and contact order in protein folding. Chiti F*, Taddei N, White PM, Bucciantini M, Magherini F, Stefani M & Dobson CM*, Nature Struct Biol 6(11), 1005-1009 1999.
  48. Microtubules switch occasionally into unfavorable conformations during elongation. Chr?tien D & Fuller SD*, J Mol Biol 299, 663-676 2000.
  49. High-resolution NMR techniques in organic chemistry. Claridge TDW*, Oxford: Pergamon, Tetrahedron Organic Chemistry; vol 19) 1999.
  50. Collectins and innate immunity in the lung. Clark HW, Reid KBM* & Sim RB*, Microbes and Infection 2, 273-278 2000.
  51. Characterisation of tissue-specific oligosaccharides from rat brain and kidney membrane preparations enriched in Na+, K+-atpase. Clark RAC, Küster B, Benallal M, Anner BM, Dwek RA*, Harvey DJ & Wing DR, Glycoconjugate J 16, 437-456 1999.
  52. Macromolecular modelling on the Cray T3D. Cooper MD, Goodfellow JM, Hillier IH, Reynolds CA, Richards WG*, Robb MA, Sherwood P & Williams IH, In: Allan RJ, Guest MF, Simpson A, Henty DS & Nicole RA, ed. High Performance Computing. New York: Kluwer Academic/Plenum Publishers, 1999.
  53. The conformation of calreticulin is influenced by the endoplasmic reticulum luminal environment. Corbett EF, Michalak KM, Oikawa K, Johnson S*, Campbell ID*, Eggleton P, Kay C & Michalak M, J Biol Chem 275(35), 27177-27185 2000.
  54. Novel oral treatment of Gaucherts disease, with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis. Cox T, Lachmann R, Hollak C, Aerts J, van Weely S, Hrebicek M, Platt FM, Butters TD, Dwek RA*, Moyses C, Gow I, Elstein D & Zimran A, Lancet 355, 1481-1485 2000.
  55. Use of composite rotations to correct systematic errors in NMR quantum computation. Cummins HK & Jones JA*, New J Phys 2, 6.1 - 6.12 2000.
  56. Crystal structure and functional dissection of the cytostatic cytokine Oncostatin M. Deller MC, Hudson KR, Ikemizu S*, Bravo J*, Jones EY* & Heath JK, Structure 8, 863-874 2000.
  57. Cell surface receptors. Deller MC* & Jones EY*, Current Opinion in Structural Biology 10(2), 213-219 2000.
  58. The glycan processing and site occupancy of recombinant Thy-1 is markedly affected by the presence of a glycosylphosphatidylinositol anchor. Devasahayam M, Catalino PD, Rudd PM, Dwek RA* & Barclay AN*, Glycobiology 9, 1381-1387 1999.
  59. Expression of the proteinase specialized in bone resorption, cathepsin K, in granulomatous inflammation. Diaz A, Willis AC* & Sim RB*, Mol Medicine 6(8), 648-659 2000.
  60. Understanding protein folding via free energy surfaces from theory and experiment. Dinner AR, Sali A, Smith LJ*, Dobson CM* & Karplus M*, Trends in Biochem Sci 25(7), 331-339 2000.
  61. How do we explore the energy landscapes for folding?. Dobson CM*, In: Fraunfelder H, Diesenhofer J & Wolynes PG, ed. Simplicity and complexity in proteins and nucleic acids, Dahlem Workshop Report. Berlin: Dahlem University Press, 15-37, 1999.
  62. The nature and significance of protein folding. Dobson CM*, In: Pain RH, ed. Mechanisms of protein folding. 2nd ed. Oxford: Oxford University Press, 1-33, 2000.
  63. Calcium binding EGF-like domains. Downing AK*, Handford PA* & Campbell ID*, In: Carafoli E & Krebs J, ed. Calcium Homeostasis. Springer Verlag, 83-99, Topics in Biological Inorganic Chemistry; vol 3. 2000.
  64. C-type lectin-like domains. Drickamer K*, Current Opinion in Structural Biology 9(5), 585-590 1999.
  65. Sugar binding in innate immunity. Drickamer K*, Taylor ME & Wallis R, Wellcome Trust Rev 9, 38-40 2000.
  66. Lung surfactant proteins involved in innate immunity. Eggleton P & Reid KBM*, Current Opinion in Immunology 11, 28-33 1999.
  67. C1q receptors. Eggleton P, Tenner AJ & Reid KBM*, Clin Exp Immunol 120, 406-412 2000.
  68. Fine specificity of autoantibodies to calreticulin: epitope mapping and characterization. Eggleton P, Ward FJ, Johnson S*, Khamashta MA, Hughes GRV, Hajela VA, Michalak M, Corbett EF, Staines NA & Reid KBM*, Clin Exp Immunol 120, 384-391 2000.
  69. Cyclin-dependent kinases: inhibition and substrate recognition. Endicott JA*, Noble MEM* & Tucker JA*, Current Opinion in Structural Biology 9(6), 738-744 1999.
  70. Removal of the N-terminal hexapeptide from human beta 2- microglobulin facilitates protein aggregation and fibril formation. Esposito G, Michelutti R, Verdone G, Viglino P, Hernandez H*, Robinson CV*, Amoresano A, Dal Piaz F, Monti M, Pucci P, Mangione P, Stoppini M, Merlini G, Ferri G & Bellotti V, Protein Science 9(5), 831-845 2000.
  71. The effects of weak magnetic fields on radical recombination reactions in micelles. Eveson RW, Timmel CR, Brocklehurst B, Hore PJ* & McLaughlin KA, Int J Radiation Biol 76, 1509-1522 2000.
  72. Syntheses of (6S)-cephalosporins from 6-aminopenicillanic acid. Fekner T, Baldwin JE*, Adlington RM, Jones TW, Prout CK* & Schofield CJ*, Tetrahedron 56(33), 6053-6074 2000.
  73. Energy transduction processes. Ferguson SJ*, In: Lederberg J, ed. Encyclopedia of Microbiology. 177-186, vol 2. 2000.
  74. Proton transfer: It's a stringent process. Ferguson SJ*, Current Biology 10(17), R627-R630 2000.
  75. Transmembrane domains of viral ion channel proteins: a molecular dynamics simulation study. Fischer WB, Forrest LR, Smith GR & Sansom MSP*, Biopolymers 53, 529-538 2000.
  76. A viral ion channel peptide: Experimental and computational studies. Fischer WB, Pitkeathly M*, Wallace BA, Forrest LR, Smith GR & Sansom MSP*, Biophys J 78(1), 131Plat 2000.
  77. Rescue of influenza A virus from recombinant DNA. Fodor E, Devenish L, Engelhardt OG, Palese P, Brownlee GG* & GarcÆa-Sastre A, J Virology 73, 9679-9682 1999.
  78. Exploring models of the influenza A M2 channel: MD simulations in a lipid bilayer. Forrest LR, Kukol A, Arkin IT, Tieleman DP & Sansom MSP*, Biophys J 78, 55-69 2000.
  79. Membrane simulations: bigger and better?. Forrest LR & Sansom MSP*, Current Opinion in Structural Biology 10, 174-181 2000.
  80. Stephen Waley - A gentleman catalyst for science. Frere JM & Schofield CJ*, Current Pharmaceutical Design 5(11), 837 1999.
  81. Virus crystallography. Fry EE, Grimes J* & Stuart DI*, Molecular Biotechnology 12(1), 13-23 1999.
  82. Cryo-electron microscopy: take back the knight. Fuller SD*, Microbiol Today 26, 56-58 1999.
  83. Distance determination in spin-correlated radical pairs in photosynthetic reaction centres by electron spin echo envelope modulation. Fursman CE & Hore PJ*, Chem Phys Lett 303, 593-600 1999.
  84. Classical and non-classical class I MHC molecules exhibit subtle conformational differences that affect binding to CD8aa. Gao GF, Willcox BE, Wyer JR, Boulter JM, O'Callaghan CA, Maenaka K*, Stuart DI*, Jones EY*, van der Merwe PA, Bell JI & Jakobsen BK, J Biol Chem 275(20), 15232-15238 2000.
  85. Cool data: Quantity and quality. Garman EF, Acta Cryst D 55, 1641-1653 1999.
  86. Leaving no element of doubt: analysis of proteins using microPIXE. Garman EF, Structure 7, R291-299 1999.
  87. Two edged role of mannose binding lectin in rheumatoid arthritis: a cross sectional study. Garred P, Madsen HO, Marquart H, Hansen TM, Sorensen SF, Petersen J, Volck B, Svejgaard A, Graudal NA, Rudd PM, Dwek RA*, Sim RB* & Andersen V, J Rheumatology 27, 26-34 2000.
  88. QSAR and molecular graphics analysis of N2-phenylguanines as inhibitors of herpes simplex virus thymidine kinases. Gaudio AC, Richards WG* & Takahata Y, J Mol Graphics & Modelling 18, 33-41 2000.
  89. Structure of human transthyretin complexed with bromophenols: a new mode of binding. Ghosh M*, Meerts IATM, Cook A, Bergman A, Brouwer A & Johnson LN*, Acta Cryst D56, 1085-1095 2000.
  90. Escherichia coli DipZ: anatomy of a transmembrane protein disulphide reductase in which three pairs of cysteine residues, one in each of three domains, contribute differentially to function. Gordon EHJ, Page MD*, Willis AC* & Ferguson SJ*, Molec Microbiol 35(6), 1360-1374 2000.
  91. Recent biomedical applications of the Oxford scanning proton microprobe. Grime GW, Palsgard E, Garman EF, Ugarte M, Pottage D & Wyeth P, International J PIXE 9, 199-216 1999.
  92. The gene machine. Groß M*, Chem in Brit 36(7), 25 2000.
  93. Le repliement rat? des prot?ines (The dangers of misfolded proteins).Groß M* & Receveur V*, Recherche (325), 51-53 1999.
  94. Crystal structure of the trimeric a-helical coiled-coil and the three lectin domains of human lung surfactant protein D. H?kansson K, Lim NK, Hoppe HJ & Reid KBM*, Structure with Folding & Design 7(3), 255-264 1999.
  95. Molecular analysis of eight mutations in FBN1. Halliday D, Hutchinson S, Kettle S, Firth H, Wordsworth BP & Handford PA*, Hum Genet 9, 1987-1994 1999.
  96. Evidence concerning rate-limiting steps in protein folding from the effects of trifluoroethanol. Hamada D*, Chiti F*, Guijarro JI*, Kataoka M, Taddei N & Dobson CM*, Nature Struct Biol 7(1), 58-61 2000.
  97. Fibrillin: From domain structure to supramolecular assembly. Handford PA*, Downing AK*, Reinhardt DP & Sakai LY, Matrix Biology 19, 457-470 2000.
  98. Matrix-assisted laser desorption/ionization mass spectrometry of N-linked carbohydrates and related compounds. Harvey DJ, Küster B, Wheeler SF, Hunter AP, Bateman RH & Dwek RA*, Mass Spectrom Biol Med, 403-437 2000.
  99. The relative orientation of the fibronectin 6F11F2 module pair: A 15N NMR relaxation study. Hashimoto Y, Smith SP, Pickford AR, Bocquier AA, Campbell ID* & Werner JM*, J Biomol NMR 17, 203-214 2000.
  100. Human apolipoprotein C-II forms twisted amyloid ribbons and closed loops. Hatters DM, MacPhee CE*, Lawrence LJ, Sawyer WH & Howlett GJ, Biochemistry 39(28), 8276-8283 2000.
  101. The crystal structure of coxsackievirus A9: new insights into the uncoating mechanisms of enteroviruses. Hendry E, Hatanaka H, Fry E, Smyth M, Tate J, Stanway G, Santti J, Maaronen M, Hyypia T & Stuart DI*, Structure with Folding & Design 7(12), 1527-1538 1999.
  102. Mutagenesis of the proposed iron-sulfur cluster binding ligands in Escherichia coli biotin synthase. Hewitson KS*, Baldwin JE*, Shaw NM & Roach PL*, FEBS Lett 466(2-3), 372-376 2000.
  103. Preparation of synthetic human islet amyloid polypeptide (IAPP) in a stable conformation to enable study of conversion to amyloid-like fibrils. Higham CE, Jaikaran ETAS, Fraser PE, Groß M* & Clark A, FEBS Lett 470, 55-60 2000.
  104. Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D. Holmskov U, Mollenhauer J, Madsen J, Vitved L, Gronlund J, Tornoe I, Kliem A, Reid KBM*, Poustka A & Skjodt K, Proc Nat Acad Sci USA 96, 10794-10799 1999.
  105. Computer prediction of transporter topology and structure. Hong R & Sansom MSP*, In: Baldwin SA, ed. Membrane Transport - A Practical Approach. OUP, 209-228, 2000.
  106. Design of MKC-442 (Emivirine) analogues with improved activity against drug resistant HIV mutants. Hopkins AL*, Ren JS, Tanaka H, Baba M, Okamato M, Stuart DI* & Stammers DK*, J Med Chem 42(22), 4500-4505 1999.
  107. NMR principles. Hore PJ*, In: Lindon JC, Tranter GE & Holmes JL, ed. Encyclopedia of spectroscopy and spectrometry. Academic Press, 1545-1553, 1999.
  108. NMR: The Toolkit. Hore PJ*, Jones JA* & Wimperis S, Oxford University Press, Oxford Chemistry Primers; vol 92) 2000.
  109. Tetrahydrofuran amino acids: Secondary structure in tetrameric and octameric carbopeptoids derived from a D-allo 5-aminomethyltetrahydrofuran-2-carboxylic acid. Hungerford NL*, Claridge TDW*, Watterson MP, Aplin RT*, Moreno A & Fleet GWJ*, J Chem Soc Perkin Trans I (21), 3666-3679 2000.
  110. Tetrahydrofuran amino acids: b- and g-azidotetrahydrofurancarboxylic acid monomers derived from D-glucoheptonolactone as building blocks for b- and g-oligopeptides. Hungerford NL* & Fleet GWJ*, J Chem Soc Perkin Trans I (21), 3680-3685 2000.
  111. Homonojirimycin analogues and their glucosides from Lobelia sessilifolia and Adenophora spp. (Campanulaceae). Ikeda K, Takahashi M, Nishida M, Miyauchi M, Kizu H, Kameda Y, Arisawa M, Watson AA, Nash RJ, Fleet GWJ* & Asano N, Carbohyd Res 323, 73-80 2000.
  112. Structure and dimerization of a soluble form of B7-1. Ikemizu S*, Gilbert RJC*, Fennelly JA, Collins AV, Harlos K*, Jones EY*, Stuart DI* & Davis SJ, Immunity 12, 51-60 2000.
  113. Carbohydrates and glycoconjugates - Editorial overview. Imberty A & Drickamer K*, Current Opinion in Structural Biology 9(5), 547-548 1999.
  114. X-ray crystallographic study of cyanide binding provides insights into the structure-function relationship for cytochrome cd1 nitrite reductase from Paracoccus pantotrophus. Jafferji A, Allen JWA, Ferguson SJ* & Fülöp V*, J Biol Chem 275(33), 25089-25094 2000.
  115. Crystallization and preliminary X-ray analysis of nitrous oxide reductase from Paracoccus pantotrophus. Jafferji A, Sami M*, Nuttall J, Ferguson SJ*, Berks BC & Fülöp V*, Acta Cryst D 56, 653-655 2000.
  116. Amyloid-like fibrils form from more than one peptide domain of human and rat islet amyloid polypeptide. Jaikaran ETAS, Higham CE, Groß M*, Fraser PE & Clark A, Diabetologia 43, 535 2000.
  117. Signal transduction proteins: structural basis of control by phosphorylation. Johnson LN*, Noble MEM*, Barford D*, Brown NR*, Endicott JA*, Lawrie A & Owen DJ*, J Chem Soc Pak 21, 185-202 1999.
  118. NMR quantum computation: a critical evaluation. Jones JA*, Fortschritte Der Physik-Progress of Physics 48(9-11), 909-924 2000.
  119. Quantum computing and NMR. Jones JA*, In: Brooks ME, ed. Quantum Computing and Communications. Springer-Verlag, 1999.
  120. Quantum computing and NMR. Jones JA*, In: D B, Ekert A & Zeilinger A, ed. The physics of quantum information. Berlin: Springer-Verlag, 2000.
  121. Efficient refocussing of one spin and two spin interactions for NMR quantum computation. Jones JA* & Knill E, J Mag Res 141(2), 322-325 1999.
  122. Geometric quantum computation using nuclear magnetic resonance. Jones JA*, Vedral V, Ekert A & Castagnoli G, Nature 403(6772), 869-871 2000.
  123. Influence of baculovirus-host cell interactions on complex N-Linked glycosylation of a recombinant human protein. Joshi L, Davis TR, Mattu TS, Rudd PM, Dwek RA*, Shuler ML & Wood HA, Biotechnology Prog 16, 650-656 2000.
  124. Localization and characterization of the hyaluronan-binding site on the Link module from human TSG-6. Kahmann JD*, O'Brien R, Werner JM*, Heinegard D, Ladbury JE, Campbell ID* & Day AJ, Structure 8(7), 763-774 2000.
  125. Structural basis of cell-cell adhesion by NCAM. Kasper C, Rasmussen H, Kastrup JS, Ikemizu S*, Jones EY*, Berezin V, Bock E & Larsen IK, Nature Struct Biol 7(5), 389-393 2000.
  126. Characterisation of fibrillin-1 cDNA clones in a human fibroblast cell line that assembles microfibrils. Kettle S, Cardy C, Hutchinson S, Sykes B & Handford PA*, Int J Biochem & Cell Biol 32, 201-214 2000.
  127. C1q: structure, function, and receptors. Kishore U & Reid KBM*, Immunopharmacology 49, 159-170 2000.
  128. Modular organization of proteins containing C1q-like globular domain. Kishore U & Reid KBM*, Immunopharmacology 42, 15-21 1999.
  129. A partially unfolded structure of the alkaline-denatured state of pepsin and its implication for stability of the zymogen-derived protein. Konno T, Kamatari YO*, Tanaka N, Kamikubo H, Dobson CM* & Nagayama K, Biochemistry 39(14), 4182-4190 2000.
  130. Oxidase reaction of cytochrome cd1 from Paracoccus pantotrophus. Koppenhofer A, Little RH, Lowe DJ, Ferguson SJ* & Watmough NJ, Biochemistry 39, 4028-4036 2000.
  131. Cytochrome cd1 from Paracoccus pantotrophus exhibits kinetically gated, conformationally dependent, highly co-operative two-electron redox behaviour. Koppenhofer A, Turner KL, Allen WA, Chapman SK & Ferguson SJ*, Biochemistry 39, 4243-4249 2000.
  132. Definition of peptide binding motifs amongst the HLA-A*30 allelic group. Krausa P, Munz C, Keilholz W, Stevanovic S, Jones EY*, Browning M, Bunce M, Rammensee H-G & McMichael A, Tissue Antigens 56, 10-18 2000.
  133. Formation and seeding of amyloid fibrils from wild-type hen lysozyme and a peptide fragment from the b-domain. Krebs MRH*, Wilkins DK, Chung EW*, Pitkeathly MC*, Chamberlain A*, Zurdo J*, Robinson CV* & Dobson CM*, J Mol Biol 300(3), 541-549 2000.
  134. Limitations in macromolecular crystallography due to radiation damage. Kuhn P, Garman EF & Soltis SM. Presented at: Synchrotron Radiation Instrumentation. Proceedings of the 11th US National Conference, SLAC, Pianetta P, Arthur J & Brennan S, ed. 215-218 1999.
  135. Simulation studies of the interaction of antimicrobial peptides and lipid bilayers. La Rocca P, Biggin PC, Tieleman DP & Sansom MSP*, Biochim Biophys Acta 1462(1-2), 185-200 1999.
  136. Past Times. Lagnado J & Williams RJP*, The Biochemist, 46-48 1999.
  137. The evolution, structure, biology and pathophysiology of complement. Lambris JD, Reid KBM* & Volanakis E, Immunol Today 20, 207-211 1999.
  138. Protein folding and interactions revealed by mass spectrometry. Last AM* & Robinson CV*, Current Opinion in Chemical Biology 3(5), 564-570 1999.
  139. Molecular modelling of human and C. elegans TW1K potassium channels. Law R, Bartlett G & Sansom MSP*, J Physiology 525(Suppl. S), 80P-81P 2000.
  140. Structure and dynamics of the pore-lining helix of the nicotinic receptor: MD simulations in water, lipid-bilayers and transbilayer bundles. Law RJ, Forrest LR, Ranatunga KM, La Rocca P, Tieleman DP & Sansom MSP*, Proteins: Structure, Function & Genetics 39(1), 47-55 2000.
  141. Genomic organization of the mouse gene for lung surfactant protein D. Lawson PR, Perkins VC, Holmskov U & Reid KBM*, Am J Respir Cell Mol Biol 20, 953-963 1999.
  142. A novel PCR-based technique using expressed sequence tags and gene homology for murine genetic mapping: localization of the complement genes. Lawson PR & Reid KBM*, Int Immunology 12, 231-240 2000.
  143. The roles of surfactant proteins A and D in innate immunity. Lawson PR & Reid KBM*, Immunologic Reviews 173, 66-78 2000.
  144. The effect of cysteine mutations on recombinant deacetoxycephalosporin C synthase from S. clavuligerus. Lee H-J*, Lloyd MD*, Harlos K* & Schofield CJ*, Biochem & Biophys Res Commun 267(1), 445-448 2000.
  145. Cyclin-dependent kinase inhibition by new C-2 alkynylated purine derivatives and molecular structure of a CDK2-inhibitor complex. Legraverend M, Tunnah P, Noble M*, Ducrot P, Ludwig O, Grierson DS, Leost M, Meijer L & Endicott J*, J Med Chem 43(7), 1282-1292 2000.
  146. Synchrotron radiation diffraction from two-dimensional protein crystals at the air/water interface. Lenne P-F, Berge B, Renault A, Zakri C, Venien-Bryan C*, Courty S, Balavoine F, Konovalov O, Brisson A, Gübel G & Legrand J-F, Biophys J 79(1), 496-500 2000.
  147. MtGimC, a novel archaeal chaperone related to the eukaryotic chaperonin cofactor GimC/prefoldin. Leroux MR, Fändrich M*, Klunker D, Siegers K, Lupas AN, Brown JR, Schiebel E, Dobson CM* & Hartl FU, EMBO J 18(23), 6730-6743 1999.
  148. Unnatural co-substrate-based rescue of enzyme activity in Refsum's disease resulting from mutations in R275 of phytanoyl-CoA hydroxylase. Lloyd MD*, Mukherji M*, Kershaw N*, MacKinnon CH*, Schofield CJ* & Wierzbicki AS, Am J Hum Genetics 67(suppl. 2, poster 1642), 297 2000.
  149. Unnatural cosubstrate-based rescue of enzyme activity in Refsum's Disease resulting from a PAHX mutation. Lloyd MD*, Mukherji M*, Kershaw N*, MacKinnon CH*, Schofield CJ* & Wierzbicki AS, J Inherit Metabol Disease 23(Suppl. 1), 516-O 2000.
  150. Chemical dissection and reassembly of amyloid fibrils formed by a peptide fragment of transthyretin. MacPhee CE* & Dobson CM*, J Mol Biol 297(5), 1203-1215 2000.
  151. Improved photo-CIDNP methods for studying protein structure and folding. Maeda K, Lyon CE*, Lopez JJ, Cemazar M, Hore PJ* & Dobson CM*, J Biomol NMR 16(3), 235-244 2000.
  152. MHC superfamily structure and the immune system. Maenaka K & Jones EY*, Current Opinion in Structural Biology 9(6), 745-753 1999.
  153. Killer cell immunoglobulin receptors and T cell receptors bind peptide-Major Histocompatibility Complex class I with distinct thermodynamic and kinetic properties. Maenaka K, Juji T, Nakayama T, Wyer JR, Gao GF, Maenaka T, Zaccai NR*, Kikuchi A, Yabe T, Tokunaga K, Tadokoro K, Stuart DI*, Jones EY* & van der Merwe PA, J Biol Chem 274(40), 28329-28334 1999.
  154. Cryo-electron microscopy reveals the functional organization of an enveloped virus, Semliki Forest virus. Mancini EJ, Clarke M, Gowen B, Rutten T & Fuller SD*, Molecular Cell 5, 255-266 2000.
  155. Supplanting crystallography or supplementing microscopy? A combined approach to the study of an enveloped virus. Mancini EJ & Fuller SD*, Acta Cryst D 56, 1278-1287 2000.
  156. Cell-specific glycoforms of sialoadhesin and CD45 are counter-receptors for the cysteine-rich domain of the mannose receptor. Martinez-Pomares L, Crocker PR, Da Silva R, Holmes N, Colominas C, Rudd PM, Dwek RA* & Gordon S, J Biol Chem 274, 35211-35218 1999.
  157. Thermal unfolding of an intermediate is associated with non-Arrhenius kinetics in the folding of hen lysozyme. Matagne A*, Jamin M, Chung EW*, Robinson CV*, Radford SE & Dobson CM*, J Mol Biol 297(1), 193-210 2000.
  158. O-Glycan analysis of natural human neutrophil gelatinase B using a combination of normal phase-HPLC and online tandem mass spectrometry: implications for the domain organisation of the enzyme. Mattu T, Royle L, Langridge J, Wormald MR, Van den Steen PE, Van Damme J, Opdenakker G, Harvey DJ, Dwek RA* & Rudd PM, Biochemistry 39, 15695-15704 2000.
  159. Signaling lymphocytic activation molecule (CDw150) is homophilic but self-associates with very low affinity. Mavaddat N, Mason DW, Atkinson PD, Evans EJ, Gilbert RJC*, Stuart DI*, Fennelly JA, Barclay AN*, Davis SJ & Brown MH, J Biol Chem 275(36), 28100-28109 2000.
  160. Molecular consequences of calcium binding mutations in Marfan syndrome depend on domain context. McGettrick AJ, Knott V*, Willis A* & Handford PA*, Hum Mol Genet 9, 1987-1994 2000.
  161. High-performance cation-exchange chromatography and pulsed amperometric detection for the separation, detection, and quantitation of n-alkylated imino sugars in biological samples. Mellor HR, Adam A, Platt FM, Dwek RA* & Butters TD, Analytical Biochem 284, 136-142 2000.
  162. Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation. Mongkolsapaya J, Grimes JM*, Chen N, Xu X-N, Stuart DI*, Jones EY* & Screation GR, Nature Struct Biol 6(11), 1048-1053 1999.
  163. A compact monomeric intermediate identified by NMR in the denaturation of dimeric triose phosphate isomerase. Morgan CJ*, Wilkins DK, Smith LJ*, Kawata Y & Dobson CM*, J Mol Biol 300(1), 11-16 2000.
  164. Amyloid fibril formation and seeding by wild type human lysozyme and its disease-related mutational variants. Morozova-Roche LA*, Zurdo J*, Spencer A*, Noppe W, Receveur V*, Archer DB, Joniau M & Dobson CM*, J Structural Biol 130(2-3), 339-351 2000.
  165. Investigation of the intracellular transport of tyrosinase and tyrosinase related protein (TRP)-1. The effect of endoplasmic reticulum (ER)-glucosidases Inhibition. Negroiu G, Branza-Nichita N, Costin GE, Titu H, Petrescu AJ, Dwek RA* & Petrescu SM, Cellular & Mol Biol 45, 1001-1010 1999.
  166. Protein specific N-glycosylation of tyrosinase and tyrosinase-related protein-1 in B16 mouse melanoma cells. Negroiu G, Branza-Nichita N, Petrescu AJ, Dwek RA* & Petrescu SM, Biochem J 344, 659-665 1999.
  167. Folding and maturation of tyrosinase-related protein-1 are regulated by the pos-translational formation of disulfide bonds and by n-glycan processing. Negroiu G, Dwek RA* & Petrescu SM, J Biol Chem 275, 32200-32207 2000.
  168. Probing the nature of amyloidogenic proteins by mass spectrometry. Nettleton EJ* & Robinson CV*. Presented at: Mass Spectrometry in Biology and Medicine, Burlingame AL, Carr SA & Baldwin MA, ed. Humana Press, Totowa, NJ, 53-72 2000.
  169. Characterization of the oligomeric states of insulin in self-assembly and amyloid fibril formation by mass spectrometry. Nettleton EJ*, Tito P*, Sunde M*, Bouchard M*, Dobson CM* & Robinson CV*, Biophys J 79(2), 1053-1065 2000.
  170. A new allosteric site on glycogen phosphorylase b as a target for drug interactions. Oikonomakos NG, Skamnaki VT, Tsitsanou KE, Gavalas NG & Johnson LN*, Structure 8(6), 575-584 2000.
  171. Iron-sulfur center of biotin synthase and lipoate synthase. Ollagnier-de Choudens S, Sanakis Y, Hewitson KS*, Roach PL*, Baldwin JE*, Munck E & Fontecave M, Biochemistry 39(14), 4165-4173 2000.
  172. Unfolding proteins by external forces and temperature: The importance of topology and energetics. Paci E* & Karplus M, Proc Nat Acad Sci USA 97(12), 6521-6526 2000.
  173. Mutational analysis of the Paracoccus denitrificans c-type cytochrome biosynthetic genes ccmABCDG: disruption of ccmC has distinct effects suggesting a role for CcmC independent of CcmAB. Page MD* & Ferguson SJ*, Microbiology 145, 3047-3057 1999.
  174. Identification of residues involved in the interaction of Staphylococcus aureus fibronectin-binding protein with the 4F15F1 module pair of human fibronectin using heteronuclear NMR spectroscopy. Penkett CJ*, Dobson CM*, Smith LJ*, Bright JR, Pickford AR*, Campbell ID* & Potts JR*, Biochemistry 39(11), 2887-2893 2000.
  175. Amyloid fibril formation by the SCR3 domain of human complement receptor 1. Pertinhez TA*, Bouchard M*, Smith LJ*, Smith RG & Dobson CM*, Biophys J 78(1), 2477Pos 2000.
  176. Initial denaturing conditions influence the slow folding phase of acylphosphatase associated with proline isomerization. Pertinhez TA*, Hamada D*, Smith LJ*, Chiti F*, Taddei N, Stefani M & Dobson CM*, Protein Science 9(8), 1466-1473 2000.
  177. Tyrosinase and glycoprotein folding: Roles of chaperones that recognize glycan. Petrescu S, Branza-Nichita N, Negroiu G, Petrescu A & Dwek RA*, Biochemistry 39, 5229-5237 2000.
  178. Glycosylation and glycoprotein folding. Petrescu S, Petrescu A, Platt FM & Dwek RA*, Wellcome Trust Rev 9, 41-42 2000.
  179. Polyuridylated mRNA synthesized by a recombinant influenza virus is defective in nuclear export. Poon LLM, Fodor E & Brownlee GG*, J Virology 74, 418-427 1999.
  180. Direct evidence that the poly(A) tail of influenza A virus mRNA is synthesized by reiterative copying of a U track in the virion RNA template. Poon LLM, Pritlove DC, Fodor E & Brownlee GG*, J Virology 73, 3473-3476 1999.
  181. The iron(II), 2-oxoacid-dependent dioxygenases and their role in metabolism. Prescott AG & Lloyd MD*, Natural Product Reports 17, 367-383 2000.
  182. Imino sugar therapy for type 1 Gaucher disease. Priestman DA, Platt FM, Dwek RA* & Butters TD, Glycobiology 10, 4-6 2000.
  183. A hairpin loop at the 5' end of influenza A virus virion RNA is required for the synthesis of poly(A)+ mRNA in vitro. Pritlove DC, Poon LLM, Devenish LJ, Leahy MB & Brownlee GG*, J Virology 73, 2109-2114 1999.
  184. Protein folding: A bridge between physics and biology. Ptitsyn OB, Finkelstein AV & Dobson CM*, Mol Biol 33(6), 893-896 1999.
  185. Computational studies on a homology model of the Shaker K+ channel pore. Ranatunga KM, Smith GR & Sansom MSP*, J Physiology 525, 86 2000.
  186. Molecular dynamics of synthetic leucine-serine ion channels in a phospholipid membrane. Randa HS, Forrest LR, Voth GA & Sansom MSP*, Biophys J 77, 2400-2410 1999.
  187. a-Lactalbumin forms a compact native-like molten globule in the absence of disulphide bonds. Redfield C*, Schulman BA, Milhollen MA, Kim PS & Dobson CM*, Nature Struct Biol 6(10), 948-952 1999.
  188. Does properdin crosslink the cellular and the humoral immune response?. Reid KBM* & Schwaeble WJ, Immunol Today 20, 17-21 1999.
  189. Molecular structure and gas-phase reactivity of zileuton and its N-dehydroxylated metabolite: two-layered ONIOM calculations. Remko M, Lyne PD & Richards WG*, Phys Chem Chem Phys 2, 2511-2514 2000.
  190. Molecular structure, gas-phase acidity and basicity of N-hydroxyurea. Remko M, Lyne PD & Richards WG*, Phys Chem Chem Phys 1, 5353-5357 1999.
  191. Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases - Structural and biochemical analyses. Ren JS, Diprose J, Warren J, Esnouf RM, Bird LE, Ikemizu S*, Slater M, Milton J, Balzarini J, Stuart DI* & Stammers DK*, J Biol Chem 275(8), 5633-5639 2000.
  192. Binding of the second generation non-nucleoside inhibitor S-1153 to HIV-1 reverse transcriptase involves extensive main chain hydrogen bonding. Ren JS, Nichols C*, Bird LE, Fujiwara T, Sugimoto H, Stuart DI* & Stammers DK*, J Biol Chem 275(19), 14316-14320 2000.
  193. Surface polymerization of actin induced on lipid monolayer. Renault A, Lenne PF, Zakri C, Aradian A, Venien-Bryan C* & Amblard F, Biophys J 76, 1580-1590 1999.
  194. Reflections at 60. Richards WG*, Internet J Chem 3, 2000.
  195. Molecular similarity. Richards WG* & Robinson DD, In: Truhlar DG, Howe WJ, Hopfinger AJ, Blaney J & Dammkoehler RA, ed. Rational Drug Design. New York: Springer-Verlag, 1999.
  196. The disassembly of macromolecular complexes using mass spectrometry. Robinson CV*, FASEB Journal 14(8), A1511 2000.
  197. Partial molecular alignment via local structure analysis. Robinson DD, Lyne PD & Richards WG*, J Chem Inf Comp Sci 40, 503-512 2000.
  198. The structures of the neurotrophin 4 homodimer and the brain- derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site. Robinson RC, Radziejewski C, Spraggon G*, Greenwald J, Kostura MR, Burtnick LD, Stuart DI*, Choe S & Jones EY*, Protein Science 8(12), 2589-2597 1999.
  199. Detection and selective dissociation of intact ribosomes in a mass spectrometer. Rostom AA*, Fucini P*, Benjamin DR*, Juenemann R, Nierhaus KH, Hartl FU, Dobson CM* & Robinson CV*, Proc Nat Acad Sci USA 97(10), 5185-5190 2000.
  200. Specificity and interactions of the protein OppA: Partitioning solvent binding effects using mass spectrometry. Rostom AA*, Tame JRH, Ladbury JE & Robinson CV*, J Mol Biol 296(1), 269-279 2000.
  201. Glycoproteomics: High-throughput sequencing of oligosaccharide modifications to proteins. Rudd PM, Colominas C, Royle L, Murphy N, Hart E, Merry AH, Heberstreit HF & Dwek RA*, Proteome Res: Mass Spectrometry 11, 207-228 2000.
  202. Hybrid and complex glycans are linked to the conserved N-glycosylation site of the third eight-cysteine domain of LTBP-1 in insect cells. Rudd PM, Downing AK*, Cadene M, Harvey DJ, Wormald MR, Weir I, Dwek RA*, Rifkin DB & Gleizes P-E, Biochemistry 39(7), 1596-1603 2000.
  203. Exploring functions for glycosylation in host defence using novel oligosaccharide sequencing technology. Rudd PM, Wormald MR & Dwek RA*, In: Kamp RM, Kyriakidis D & Choli-Papadopoulou T, ed. Proteome & Prot Anal. Berlin, Germany: Springer-Verlag, 321-339, 2000.
  204. Hydrophobicity plots. Sansom MSP*, In: Encyclopedia of Life Sciences. Macmillan, 2000.
  205. Potassium channels: Putting the parts together. Sansom MSP*, Current Biology 9, R738-741 1999.
  206. Potassium channels: Watching a voltage-sensor tilt and twist. Sansom MSP*, Current Biology 10, R206-209 2000.
  207. Modelling transmembrane helix bundles by restrained MD simulations. Sansom MSP* & Davison L, In: Webster DM, ed. Protein Structure Prediction: Methods and Protocols. Humana Press, Methods in Molecular Biology; vol 143. 2000.
  208. Simulations of ion channels - watching ions and water move. Sansom MSP*, Shrivastava IH, Ranatunga KM & Smith GR, Trends in Biochem Sci 25, 368-374 2000.
  209. The mechanism of channel formation by alamethicin as viewed by molecular dynamics simulations. Sansom MSP*, Tieleman DP & Berendsen HJC. Presented at: Novartis Foundation Symposium, vol 225, 128-145 1999.
  210. Transcriptional analysis of the nirS gene, encoding cytochrome cd(1) nitrite reductase, of Paracoccus pantotrophus LMD 92.63. Saunders NFW, Ferguson SJ* & Baker SC, Microbiology 146, 509-516 2000.
  211. Book Review: D-Amino acids in sequences of secreted peptides of multicellular organisms, edited by Pierre Jolles. Schofield CJ, Protein Science 8(8), 1720 1999.
  212. Book Review: Introduction to flavonoids, edited by Bruce A. Bohm. Schofield CJ* & Turnbull J*, Natural Product Reports 17(5), 505 2000.
  213. Structural and mechanistic studies on 2-oxoglutarate-dependent oxygenases and related enzymes. Schofield CJ* & Zhang ZH*, Current Opinion in Structural Biology 9(6), 722-731 1999.
  214. Bis(1,3-dihydroxy-isopropyl)amine (BDI) as an AB4 dendritic building block: rapid synthesis of a second generation dendrimer. Scott DA, Krülle TM*, Finn M* & Fleet GWJ*, Tet Lett 41(20), 3959-3962 2000.
  215. Synthesis of bis(1,3-dihydroxy-isopropyl)amine by reductive amination of dihydroxyacetone: Open chain equivalent of DMDP and a potential AB4 dendritic monomer. Scott DA, Krülle TM*, Finn M*, Nash RJ, Winters AL, Asano N, Butters TD & Fleet GWJ*, Tet Lett 40(42), 7581-7584 1999.
  216. Structure and dynamics of K channel pore-lining helices: a comparative simulation study. Shrivastava I, Capener C, Forrest LR & Sansom MSP*, Biophys J 78, 79-92 2000.
  217. Simulations of ion permeation through a potassium channel: molecular dynamics of KcsA in a phospholipid bilayer. Shrivastava IH & Sansom MSP*, Biophys J 78, 557-570 2000.
  218. Structure of arylamine N-acetyltransferase reveals a catalytic triad. Sinclair JC, Sandy J, Delgoda R, Sim E & Noble MEM*, Nature Struct Biol 7(7), 560-564 2000.
  219. Catalytic mechanism of phosphorylase kinase probed by mutational studies. Skamnaki VT, Owen DJ*, Noble MEM*, Lowe ED*, Oikonomakos NG & Johnson LN*, Biochemistry 38(44), 14718-14730 1999.
  220. Designing secondary structures: 5-azidomethyl tetrahydrofuran- 2-carboxylates as carbohydrate-derived dipeptide isosteres. Smith MD & Fleet GWJ*, J Peptide Sci 5(10), 425-441 1999.
  221. Interface characterization of the type II module pair from fibronectin. Smith SP, Hashimoto Y, Pickford AR, Campbell ID* & Werner JM*, Biochemistry 39(29), 8374-8381 2000.
  222. Reduced levels of neuraminidase of influenza A viruses correlate with attenuated phenotypes in mice. Solorzano A, Zheng H, Fodor E, Brownlee GG*, Palese P & Garcia-Sastre A, J General Virology 81, 737-742 2000.
  223. Simulation of the packing of idealised transmembrane a-helix bundle. Son HS & Sansom MSP*, Eur Biophys J 28(6), 489-498 1999.
  224. Simulation studies on bacteriorhodopsin a-helices. Son HS & Sansom MSP*, Eur Biophys J 28(8), 674-682 2000.
  225. Simulation studies on bacteriorhodopsin bundle of transmembrane a-segments. Son HS & Sansom MSP*, Eur Biophys J 28(8), 663-673 2000.
  226. An anion-selective analogue of the channel-forming peptide alamethicin. Starostin AV, Butan R, Borisenko RV, James DA, Wenschuh H, Sansom MSP* & Woolley GA, Biochemistry 38(19), 6144-6150 1999.
  227. Radiofrequency magnetic field effects on chemical reaction yields. Stass DV, Woodward JR, Timmel CR, Brocklehurst B, Hore PJ* & McLaughlin KA, Chem Phys Lett 329, 15-22 2000.
  228. Crystallography of viruses and very large macromolecules. Stuart DI*, Grimes JM* & Fry EE, In: Fanchon, Geissler, Hodeau, Regnard & Timmins, ed. Structure and dynamics of biomolecules. Oxford University Press, 353-366, Hercules course; vol IV. 2000.
  229. Stabilisation of a-helices by site-directed mutagenesis reveals the importance of secondary structure in the transition state for acylphosphatase folding. Taddei N, Chiti F*, Fiaschi T, Bucciantini M, Capanni C, Stefani M, Serrano L, Dobson CM* & Ramponi G, J Mol Biol 300(3), 633-647 2000.
  230. The structure and dynamics in solution of Cu(I) pseudoazurin from Paracoccus pantotrophus. Thompson GS, Leung YC*, Ferguson SJ*, Radford SE & Redfield C*, Protein Science 9(5), 846-858 2000.
  231. Surface binding of alamethicin stabilises its helical structure: molecular dynamics simulations. Tieleman DP, Berendsen HJC & Sansom MSP*, Biophys J 76, 3186-3191 1999.
  232. Electrospray time-of-flight mass spectrometry of the intact MS2 virus capsid. Tito MA*, Tars K, Valegard K, Hajdu J* & Robinson CV*, J Am Chem Soc 122(14), 3550-3551 2000.
  233. Dissecting the hydrogen exchange properties of insulin under amyloid fibril forming conditions: a site-specific investigation by mass spectrometry. Tito P*, Nettleton EJ* & Robinson CV*, J Mol Biol 303, 267-278 2000.
  234. Conversion of a c type cytochrome to a b type that spontaneously forms in vitro from apo protein and heme: Implications for c type cytochrome biogenesis and folding. Tomlinson EJ & Ferguson SJ*, Proc Nat Acad Sci USA 97(10), 5156-5160 2000.
  235. Time-resolved CIDNP and laser flash photolysis study of the photoreactions of N-acetyl histidine with 2,2 '-dipyridyl in aqueous solution. Tsentalovich YP, Morozova OB, Yurkovskaya AV, Hore PJ* & Sagdeev RZ, J Phys Chem A 104(30), 6912-6916 2000.
  236. Effects of macromolecular crowding on protein folding and aggregation. van den Berg B*, Ellis RJ & Dobson CM*, EMBO J 18(24), 6927-6933 1999.
  237. Macromolecular crowding perturbs protein refolding kinetics: implications for folding inside the cell. van den Berg B*, Wain R*, Dobson CM* & Ellis RJ, EMBO J 19(15), 3870-3875 2000.
  238. Porcine lung surfactant protein D: complementary DNA cloning, chromosomal localization, and tissue distribution. Van Eijk M, Haagsman HP, Skinner T, Archibold A, Reid KBM* & Lawson PR, J Immunology 164, 1442-1450 2000.
  239. Modelling the catalytic reaction in human aldose reductase. Varnai P, Richards WG* & Lyne PD, Proteins: Structure, Function & Genetics 37, 218-227 1999.
  240. Can a pairwise contact potential stabilize native protein folds against decoys obtained by threading?. Vendruscolo M*, Najmanovich R & Domany E, Proteins: Structure, Function & Genetics 38(2), 134-148 2000.
  241. Projection structure of a transcriptional regulator, HupR, determined by electron cryo-microscopy. Venien-Bryan C*, Schertler GFX, Thouvenin E & Courty S, J Mol Biol 296(3), 863-871 2000.
  242. Altered protein aggregation. Villegas V, Zurdo J*, Aviles FX, Dobson CM* & Serrano L, British patent application Patent: 9924484.0 (International application PCT/GB00/03974) 1999.
  243. Protein engineering as a strategy to avoid formation of amyloid fibrils. Villegas V, Zurdo J*, Filimonov VV, Aviles FX, Dobson CM* & Serrano L, Protein Science 9(9), 1700-1708 2000.
  244. The reaction of TMS-CF3 with amino acid derived ring-templates: studies with oxazin-2-ones and oxazolidin-5-ones. Walter MW*, Thaker N, Baldwin JE*, Muller M & Schofield CJ*, J Chem Res (S) (7), 310-311 2000.
  245. Backbone dynamics of a cbEGF domain pair in the presence of calcium. Werner JM*, Knott V, Handford PA*, Campbell ID* & Downing AK*, J Mol Biol 296(4), 1065-1078 2000.
  246. Drosophila Dumpy is a gigantic extracellular protein required to maintain tension at epidermal-cuticle attachment sites. Wilkin MB, Becker MN, Mulvey D, Phan I*, Chao A, Cooper K, Chung H-J, Campbell ID*, Baron M & MacIntyre R, Current Biology 10, 559-567 2000.
  247. Biophysical studies of the development of amyloid fibrils from a peptide fragment of cold shock protein B. Wilkins DK, Dobson CM* & Groß M*, Eur J Biochem 267(9), 2609-2616 2000.
  248. Hydrodynamic radii of native and denatured proteins measured using pulse field gradient NMR techniques. Wilkins DK, Grimshaw SB*, Receveur V*, Dobson CM*, Jones JA* & Smith LJ*, Biochemistry 38, 16424-16431 1999.
  249. Production of soluble ab T-cell receptor heterodimers suitable for biophysical analysis of ligand binding. Willcox BE, Gao GF, Wyer JR, O'Callaghan CA, Boulter JM, Jones EY*, van der Merwe PA, Bell JI & Jakobsen BK, Protein Science 8, 2418-2423 1999.
  250. Bringing chemistry to life. Williams RJP*, Chem Rev 9(3), 19-23 1999.
  251. Calcium homeostasis and its evolution. Williams RJP*, In: Carafoli E & Krebs J, ed. Calcium Homeostasis. Springer Verlag, 1-28, Topics in Biological Inorganic Chemistry; vol 3. 2000.
  252. The inorganic chemistry of life. Williams RJP*, In: Hall N, ed. The New Chemistry. Cambridge University Press, Ch 11, 259-299, 2000.
  253. Membrane Transport, Bioenergetics and History (Commentary). Williams RJP*, Quart Rev Biol 74(4), 443-445 1999.
  254. Mitochondria and chloroplasts: localized and delocalized bioenergetic transduction. Williams RJP*, Trends in Biochem Sci 25, 479 2000.
  255. A survey of the Sixth European Symposium on Calcium-binding Proteins Calcium: its flow, its proteins and genome. Williams RJP*, Biochim Biophys Acta 1498, 82-83 2000.
  256. What is wrong with aluminium? The J.D. Birchall memorial lecture. Williams RJP*, J Inorg Biochem 76, 81-88 1999.
  257. Bringing chemistry to life. Williams RJP* & Frausto da Silva JJR, Oxford: Oxford University Press, 1999.
  258. The distribution of elements in cells. Williams RJP* & Frausto da Silva JJR, Coord Chem Rev 200-202, 247-348 2000.
  259. Recent successes in time-resolved protein crystallography. Wilmouth RC*, Clifton IJ* & Neutze R, Natural Product Reports 17(6), 527-533 2000.
  260. Reaction of clavams with elastase reveals a general method for inhibiting 'serine' enzymes. Wilmouth RC*, Li Y-H, Wright PA*, Claridge TDW*, Aplin RT* & Schofield CJ*, Tetrahedron 56(31), 5729-5733 2000.
  261. Modification of glycosylation as a therapeutic strategy. Winchester B & Fleet GWJ*, J Carbohyd Chem 19, 471-483 2000.
  262. Copper refolding of prion protein. Wong BS, Venien-Bryan C*, Williamson RA, Burton DR, Gambetti P, Sy MS, Brown DR & Jones IM, Biochem & Biophys Res Commun 276(3), 1217-1224 2000.
  263. Engineering charge selectivity in alamethicin channels. Woolley GA, Starostin AV, Butan R, James DA, Wenschuh H & Sansom MSP*. Presented at: Novartis Foundation Symposium, vol 225, 128-145 1999.
  264. Identification of amino acid residues that determine pH dependence of ligand binding to the asialoglycoprotein receptor during endocytosis. Wragg S & Drickamer K*, J Biol Chem 274(50), 35400-35406 1999.
  265. Mass spectrometry reveals elastase inhibitors from the reactive centre loop of alpha(1)-antitrypsin. Wright PA*, Rostom AA*, Robinson CV* & Schofield CJ*, Bioorganic & Medicinal Chem Lett 10(11), 1219-1221 2000.
  266. Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase. Zhang Z*, Ren J, Stammers DK*, Baldwin JE*, Harlos K* & Schofield C*, Nature Struct Biol 7(2), 127-133 2000.
  267. Model proteins to understand amyloid fibril formation. Zurdo J*, Villegas V, Aviles FX, Serrano L & Dobson CM*, Biophys J 78(1), 2478Pos 2000.

Other OCMS Members and staff publications lists:

2000/2001 - 1999/2000 - 1998/1999 - 1997/1998 - 1996/1997 - 1995/1996

Information updated 29th March 2001 by Lindsay Battle, OCMS Information Officer.

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